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Additions and changes to HIV comedications

Tuesday 23 April 2019

Some new HIV drugs and combinations have been added to the list of comedications, along with some changes to two of the existing HIV drugs.


Two new HIV drugs have been added (doravirine and ibalizumab) and five new combinations are now included:

  • darunavir/cobicistat/emtricitabine/tenofovir alafenamide
  • dolutegravir/rilpivirine
  • doravirine/lamivudine/tenofovir-DF
  • emtricitabine/tenofovir-DF
  • rilpivirine/emtricitabine/tenofovir alafenamide


Atazanavir and darunavir have been expanded according to whether they are used on their own (atazanavir only) or with cobicistat or ritonavir (atazanavir and darunavir). As cobicistat is now listed with its licensed combinations, it has been removed from the listing as a separate comedication.


The printable Overview of Interactions charts have updated and are available in the Prescribing Resources section of the website.

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