Interaction Checker

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New Additions to the Contraceptives and Hormone Replacement class

Monday 03 February 2020

We have expanded the list of contraceptive and HRT comedications available on the checker, and updated the names to make it clear if the drug is coformulated with an estrogen. The following comedications have been added:


  • Conjugated estrogens (HRT)
  • Desogestrel/ethinylestradiol (COC)
  • Drospirenone/ethinylestradiol (COC) 
  • Drospirenone/estradiol (HRT) 
  • Dydrogesterone/estradiol (HRT) 
  • Gestodene/ethinylestradiol (COC) 
  • Medroxyprogesterone/conjugated estrogens (HRT) 
  • Medroxyprogesterone/estradiol (HRT) 
  • Medroxyprogesterone (oncology) 
  • Norelgestromin/ethinylestradiol (patch) 
  • Norethisterone (Norethindrone)/ethinylestradiol (COC) 
  • Norethisterone (Norethindrone)/mestranol (COC) 
  • Norethisterone (Norethindrone) (POP) 
  • Norethisterone (Norethindrone) (depot injection) 
  • Norethisterone (Norethindrone)/estradiol (HRT) 
  • Norgestimate/ethinylestradiol (COC) 
  • Norgestrel/ethinylestradiol (COC) 
  • Norgestrel/conjugated estrogens (HRT) 


The Overview of Interactions charts have been updated and an update for the app is available to download.


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